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CHAPTER 18 - FEMALE REPRODUCTIVE SYSTEM
Histology Guide
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MICROSCOPE SLIDE

SLIDE NAME
MH 175 Placenta
TISSUE
Placenta
STAIN
Hematoxylin & Eosin
IMAGE SIZE
63,460 x 41,048 pixels
9.7 GB
FILE SIZE
499 MB
OBJECTIVE
40x
PIXEL SIZE
0.3171 µm
SOURCE
Department of Genetics, Cell Biology, and Development
School of Medicine
University of Minnesota
Minneapolis, MN

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University of Minnesota
Department of Genetics, Cell Biology and Development
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321 Church St SE
Minneapolis, MN 55455

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MH 175 Placenta

Placenta

The placenta develops from both fetal (chorion) and maternal (decidua basalis) tissues. This allows the exchange of nutrients and waste between the fetal and maternal circulations.

The placenta is composed of 15 to 20 regions called cotyledons. This specimen is a portion of a cotyledon from late pregnancy.

  • - projections of the fetal chorion that extend into lacunae in which maternal blood flows. Exchange between the two circulations occurs through the villus wall.
    • - consists of two types of cells:
      • Cytotrophoblasts - cuboidal cells with pale staining cytoplasm and euchromatic nuclei. They are absent by mid to late pregnancy so are not seen in this specimen.
      • - multinucleated cuboidal cells with microvilli.
    • - mesenchymal connective tissue forms the core of villi and contains fetal capillaries and venules.
  • - develop from arteries in the endometrium to supply maternal blood to the lacunae.
  • (Stratum Basalis) - the part of the uterus to which chorionic villi are anchored. This specimen contains only a portion of the basal plate.
    • - clusters of large round or oval cells.

Fetal and maternal blood do not mix in the placenta.

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