Histology Guide

virtual microscopy laboratory

Chapter 4 - Muscle Tissue

Muscle tissue is composed of cells that maintain the contractile function of connective tissue. Three types of muscle tissue are recognized based on their structure, function, and location:

In all types of muscle, contraction is caused by the movement of myosin filaments along actin filaments .

The terms muscle fiber and muscle cell are synonymous.

Skeletal Muscle

Skeletal muscle fibers , also known as myofibers, are long, cylindrical cells that are quite large, often spanning the entire length of a muscle.

A sarcomere is the fundamental contractile unit of striated muscle fibers.

high magnification of a sarcomere
Sarcomere
Longitudinal Section
TEM
cross section of a sarcomere
Sarcomere
Cross Section
TEM
deep etching of a sarcomere
Sarcomere
SEM (deep etching)

Cardiac Muscle

Cardiac muscle cells has branching fibers, a single, centrally located nucleus, show the same striations as skeletal muscle, and are under involuntary control.

longitudinal sections of cardiac muscle cells
Longitudinal Section
TEM
cross section of cardiac muscle cells
Cross-Section
TEM

Cardiac muscle cells are joined by specialized structures known as intercalated discs . These discs are unique to cardiac tissue and help maintain strong mechanical connections and pass electrical impulses between cells.

sarcomeres and intercalated discs
Sarcomere / Intercalated Disc
TEM
sarcomeres and intercalated discs
Sarcomere / Intercalated Disc
SEM
sarcomeres and intercalated discs
Sarcomere / Intercalated Disc
SEM

Smooth Muscle

Smooth muscle cells are spindle-shaped (fusiform), have a single, centrally located nucleus, lack striations, and are under involuntary control.

relaxed and contracted smooth muscle cells
Relaxed and Contracted
SEM
longitudinal section of a smooth muscle cell
Longitudinal Section
TEM
cross section of smooth muscle cells
Cross-Section
TEM
cross section of smooth muscle cells
Cross-Section
TEM